Authorized February 28, 1776 in the South Carolina State Troops as the 6th South Carolina Regiment. Organized in spring 1776 at Charleston to consist of five companies from northwestern South Carolina. Adopted March 25, 1776 into the Continental Army and assigned to the Southern Department.

Reorganized October 18, 1776 to consist of six companies (Captain Richbourg's Independent Company, organized in spring 1776 at Charleston with personnel from northwestern South Carolina, concurrently redesignated as the 6th Company, 6th South Carolina Regiment).

Assigned November 23, 1776 to the 1st South Carolina Brigade, an element of the Southern Department. Relieved January 3, 1779 from the 1st South Carolina Brigade. Assigned February 1, 1779 to the South Carolina Brigade, an element of the Southern Department.

Consolidated February 11, 1780 with the 2nd South Carolina Regiment [see 2nd South Carolina Regiment].

Engagements:

Charleston 1775-1776
Cherokees 1776
Florida 1778
Savannah