Isaac Huger was born on March 19, 1742 at Limerick Plantation, SC, and he died October 17, 1797. He married Elizabeth Chalmers and they had eight children.

After receiving an education in Europe, Isaac Huger was commissioned lieutenant in a battalion raised by the colony, and commanded by Col. Thomas Middleton, for service against the Cherokee Indians in 1760. At the beginning of the Revolutionary war he was made lieutenant colonel of the 1st Regiment, and in 1776 was promoted to the colonelcy of the 5th Regiment, South Carolina continental line. He was commissioned a Brigadier General in the Continental Army, 9 January, 1779, and participated in every battle of consequence fought by the southern army.

He opposed the invasion of Georgia by General Archibald Campbell, commanded the left wing at the battle of Stono Ferry, 20 June, 1779, and was wounded while leading his men. He also led the Georgia and South Carolina militia in the unsuccessful attack on Savannah, and during the Siege of Charleston was employed with a body of light troops to cut off supplies from the enemy and keep open communication between the town and country, but his force was defeated and dispersed by Colonel Banastre Tarleton and Colonel Webster at Moncks Corner, South Carolina.

He joined the army of Major General Nathanael Greene, and commanded the Virginians at the battle of Guilford Court House, where he was severely wounded. At Hobkirk's Hill, he commanded the right wing of the army. On the restoration of peace he was made vice president, and Major General Moultrie president, of the Society of the Cincinnati of the state of South Carolina.