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Authorized November 14, 1775 in the South Carolina Provincial Troops as the 4th South Carolina Regiment. Organized November 20 to December 18, 1775 at Charleston to consist of three companies from the greater Charleston area. Adopted June 18, 1776 into the Continental Army and assigned to the Southern Department.

Expanded October 18, 1776 to consist of six companies (Beaufort and Georgetown Independent Companies of Artillery concurrently redesignated as the 4th and 5th Companies, 4th South Carolina Regiment). Captured May 12, 1780 at Charleston by the British Army. Disbanded January 1, 1781.

The Beaufort Independent Company of Artillery was authorized February 22, 1776 in the South Carolina State Troops. Organized in spring 1776 at Fort Lyttleton with personnel from St. Helena and Prince William Parishes. Redesignated October 18, 1776 as the 4th Company, 4th South Carolina Regiment, and adopted into the Continental Army.

The Georgetown Independent Company of Artillery was authorized February 22, 1776 in the South Carolina State Troops. Organized in spring 1776 at Georgetown with personnel from Prince George Winyah Parish. Redesignated October 18, 1776 as the 5th Company, 4th South Carolina Regiment, and adopted into the Continental Army.

Engagements:

Charleston 1775-1776
Savannah
Charleston 1780

Detachments additionally served in the following:

Southern Highlands
Florida 1778